REBLOZYL® (luspatercept-aamt) is a prescription medicine used to treat anemia (low red blood cells) without previous erythropoiesis stimulating agent use (ESA-naïve) in adult patients with very low- to intermediate-risk myelodysplastic syndromes (MDS) who may require regular red blood cell (RBC) transfusions.
It is not known if REBLOZYL is safe or effective in children under 18 years of age.
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Anemia is one of the most common symptoms of BT and one that you may feel the most. Your anemia may make you feel tired or weak and can impact your ability to do everyday tasks and activities. It can also have long-term impacts on your health and well-being.
Anemia is a condition where you don’t have enough healthy red blood cells (RBC). This means your blood has lower than normal hemoglobin (Hgb)
levels. Hgb is an important part of an RBC. It is the part of the cell that brings oxygen to your body and organs.
In BT, ineffective erythropoiesis (IE) leads to RBCs piling up in your bone marrow.
You can learn more about IE here.
RBCs pile up when they are not able to fully mature and enter the bloodstream to do their job. This can lead to your body making too few mature, working RBCs that also may not live as long. This can lead to anemia.
You may require more or fewer RBC transfusions depending on the severity of your BT. If you have questions about this, be sure to talk to your healthcare team. They can help you identify next steps and potential treatment options.
Common symptoms of anemia include:
There are also effects of anemia associated with BT that you may not be able to see. These include: