REBLOZYL® (luspatercept-aamt) logo


REBLOZYL® (luspatercept-aamt) is a prescription medicine used to treat anemia (low red blood cells) in adults with myelodysplastic syndromes with ring sideroblasts (MDS-RS) or myelodysplastic/myeloproliferative neoplasms with ring sideroblasts and thrombocytosis (MDS/MPN-RS-T) who need regular RBC transfusions and have not responded well to or cannot receive an erythropoiesis stimulating agent (ESA).

REBLOZYL is not for use as a substitute for RBC transfusions in people who need immediate treatment for anemia.

It is not known if REBLOZYL is safe or effective in children under 18 years of age.

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Anemia plays a role in myelodysplastic syndromes (MDS)

Anemia is one of the symptoms of MDS that you may feel the most. Your anemia may make you feel tired or weak and can impact your ability to do everyday tasks and activities. It can also have long-term impacts on your health and well-being.

How does anemia in MDS happen?

Anemia is a condition that happens when you don’t have enough working RBCs. Working RBCs bring oxygen to the organs in your body.

Your healthcare team may tell you that your blood cell count is low. This may seem alarming at first, but there are options to help you manage the symptoms. Your team will help you identify what type of low blood count you are experiencing and next steps.

How can anemia impact my everyday life?

Living with anemia symptoms can be frustrating and discouraging. They can get in the way of your daily activities. You may feel too tired to go to the store or too weak to complete your usual tasks.

How can anemia impact my future health?

Anemia does not only affect your daily life, but it can also cause problems over time. For example, anemia may affect how well your intestines, heart, and lungs work. That’s why it is important to manage your anemia.

Hypothetical patient with anemia in myelodysplastic syndromes with ring sideroblasts (MDS-RS)

When anemia is left untreated, there can be long-term problems for your health and other areas of your life.

It may not feel important to give your healthcare team an update on how you are feeling. However, this is helpful information when tracking your symptoms. You can always share how you’re feeling and any symptoms you are experiencing with them. For tips on talking to your healthcare team, download our Doctor Discussion Guide.