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How do I receive REBLOZYL?

REBLOZYL will be given to you by a healthcare professional

  • REBLOZYL is given as an injection under the skin (subcutaneous) with a needle. Needles used for injections under the skin are smaller than those used for injections into muscle (intramuscular)
  • Your healthcare provider will prescribe REBLOZYL in a dose that is right for you. Your healthcare provider will calculate the exact dose of REBLOZYL you will need based on your weight, and you will receive it once every 3 weeks in a doctor’s office
  • Your doctor or another healthcare provider will check your hemoglobin levels each time before you receive REBLOZYL, and may increase or decrease your dosing amount or adjust your dosing schedule based on the results
  • If your scheduled REBLOZYL dose is delayed or missed, your healthcare provider will give your dose of REBLOZYL as soon as possible and continue your treatment as prescribed with at least 3 weeks between doses

Where will REBLOZYL be injected?

  • REBLOZYL is given as an injection under your skin (subcutaneous) by your healthcare provider
    • The injection may be given in the upper arm, thigh, or abdomen
Graphic of a body with highlights where REBLOZYL will be injected Graphic of a body with highlights where REBLOZYL will be injected

How long might I receive treatment with REBLOZYL?

You should receive REBLOZYL as long as your doctor finds it is working for you and you are able to tolerate any potential side effects that may occur

  • Your healthcare provider may adjust your dose or stop treatment depending on how you respond to REBLOZYL
  • Your healthcare provider will decide when you should receive REBLOZYL based on your response, which will include your current symptoms and any reduction in your need for red blood cell transfusions, so be sure to follow his or her instructions
  • Your healthcare provider may consider a dose increase based on how you respond to REBLOZYL
  • Your healthcare provider may also decrease your dose or stop your dose if you experience certain side effects or no reductions in transfusions

What was the dosing experience in the clinical trial?

In the clinical trial, more than half of the patients received REBLOZYL for at least 63.3 weeks

Side effects caused 2.7% of patients to have a reduced dose of REBLOZYL and 15.2% to have a dose of REBLOZYL interrupted

Almost half (46%) of patients who received REBLOZYL had their dose increased

5.4% of patients discontinued REBLOZYL due to side effects

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